Search results for "genetics [Transcriptome]"

showing 10 items of 3033 documents

4,4,4′,4′,7,7′-Hexamethyl-2,2′-spirobichroman

2000

The title compound, C23H28O2, was obtained from the reaction of acetone with meta-cresol. The molecular structure consists of two identical subunits which are nearly perpendicular to each other. The oxygen-containing rings are not planar and the molecule is chiral. The crystal structure consists of chains of molecules of the same chirality arranged along the [010] axis.

CrystallographyPlanarBicyclic moleculeChemistryPerpendicularMoleculeGeneral MedicineCrystal structurePhysics::Chemical PhysicsChirality (chemistry)General Biochemistry Genetics and Molecular BiologyActa Crystallographica Section C Crystal Structure Communications
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Structure of the new mineral sarrabusite, Pb5CuCl4(SeO3)4, solved by manual electron-diffraction tomography.

2012

The new mineral sarrabusite Pb5CuCl4(SeO3)4 has been discovered in the Sardinian mine of Baccu Locci, near Villaputzu. It occurs as small lemon–yellow spherical aggregates of tabular crystals (< 10 µm) of less than 100 µm in diameter. The crystal structure has been solved from and refined against electron diffraction of a microcrystal. Data sets have been measured by both a manual and an automated version of the new electron-diffraction tomography technique combined with the precession of the electron beam. The sarrabusite structure is monoclinic and consists of (010) layers of straight chains formed by alternating edge-sharing CuO4Cl2 and PbO8 polyhedra parallel to the c axis, which sha…

CrystallographyPolyhedronElectron diffractionZigzagChemistryCathode rayPrecessionPrecession electron diffractionGeneral MedicineCrystal structureGeneral Biochemistry Genetics and Molecular BiologyMonoclinic crystal systemActa crystallographica. Section B, Structural science
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Charge-density analysis of 1-nitroindoline: refinement quality using free R factors and restraints. Corrigendum

2011

The D e (dissociation energy) values in Table 6 of the article by Zarychta et al. [(2011). Acta Cryst. B67, 250–262] are corrected.

CrystallographyQuality (physics)ChemistryIntermolecular forceThermodynamicsCharge densityGeneral MedicineTable (information)Bond-dissociation energyGeneral Biochemistry Genetics and Molecular BiologyActa Crystallographica Section B Structural Science
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X-ray structure study of the light-induced metastable states of the spin-crossover compound [Fe(mtz)6](BF4)2

2001

Iron(II) complexes exhibiting thermal spin-crossover may be converted from the1A1low-spin (LS) state to the5T2high-spin (HS) state by irradiation with green light (light-induced excited spin-state trapping, LIESST) and from the LS to the HS state by irradiation with red light (reverse LIESST). The lifetime of the metastable LIESST states may be sufficiently long to enable an X-ray diffraction study. The lattice parameters of a single crystal of [Fe(mtz)6](BF4)2(mtz = methyltetrazole) (space groupP21/n) were measured between 300 and 10 K. While one Fe lattice site (A) of the crystal changes from the HS to the LS state near 78 K, the other site (B) remains in the LS state. Using the green lig…

CrystallographySpin statesSpin crossoverChemistryStereochemistryExcited stateMetastabilitySpin transitionCrystal structureSingle crystalGeneral Biochemistry Genetics and Molecular BiologyLIESSTJournal of Applied Crystallography
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N,N,N',N'‐Tetramethylguanidinium tetrachloroantimonate(III) at 295 and 92K

1999

The crystal structure of N,N,N',N'-tetramethylguanidinium tetrachloroantimonate(III), (C 5 H 14 N 3 )[SbCl 4 ], has been determined at 295 and 92 K. Each Sb atom is surrounded by six Cl atoms forming an irregular [SbCl 6 ] 3- octahedron. The octahedra are connected with each other in infinite zigzag chains. There is one crystallographically independent N,N,N',N'-tetramethylguanidinium cation in the crystal structure. It is linked to the [SbCl 6 ] 3- octahedra through N-H...Cl hydrogen bonds. The deformation of the octahedral coordination of the Sb III atom is related to the presence of N-H...Cl hydrogen bonds.

CrystallographyZigzagOctahedronStereochemistryChemistryHydrogen bondAtomMoleculeGeneral MedicineCrystal structureGeneral Biochemistry Genetics and Molecular BiologyActa Crystallographica Section C-Crystal Structure Communications
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Bis(6-thioxo-1,6-dihydropurinium) tetrachlorozincate(II).

2006

The title salt, (C(5)H(5)N(4)S)(2)[ZnCl(4)], consists of two 6-thioxo-1,6-dihydropurinium (6mpH(2)(+)) cations (A and B) and a tetrachlorozincate anion, which are held together by N-H...Cl and C-H...Cl interactions. There is an anion-pi interaction between one Cl atom of the [ZnCl(4)](-) anion and the pyrimidine ring of the 6mpH(2)(+)(B) cation. Intermolecular pi-pi stacking interactions allow 6mpH(2)(+)(A) cations to form antiparallel pairs. One interesting structural feature is the double N-H...N intermolecular hydrogen bonds between two 6mpH(2)(+)(A) cations. This kind of interaction, mimicking that of natural nucleobases, can be very valuable in designing new therapeutic purine derivati…

Crystallographychemistry.chemical_compoundPyrimidineHydrogen bondChemistryIntermolecular forceStackingGeneral MedicineCrystal structureAntiparallel (biochemistry)Ring (chemistry)General Biochemistry Genetics and Molecular BiologyNucleobaseActa crystallographica. Section C, Crystal structure communications
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Antitumoral activity of curcumin: an adjuvant therapeutic strategy

2021

Curcumin, an active substance contained in an Indian spice called turmeric or curcuma, is well known for its anti-inflammatory and antioxidant properties. In recent times, it was taken into account and studied as an antitumoral molecule, by relying on its interference on several biological mechanisms, such as the inhibition of inflammatory mediators, the enhancement of detoxifying enzymes’ action and processes of cell growth and proliferation. Studies show how the high dosage of curcumin in vitro inhibits colorectal tumor cells, pancreatic tumor cells, lung cancer cells and glioblastoma’s cells, interfering in signaling pathways as Wnt/β-catenin, NF-kB and PI3K/Akt and leading to cell cycle…

Curcumincolorectal tumors antioxidants curcumin antinflammatory effects pancratic cancerbusiness.industryBiochemistry (medical)Plant SciencePharmacologyGeneral Biochemistry Genetics and Molecular Biologychemistry.chemical_compoundnutritionSettore MED/03 - Genetica Medicachemistrycolon cancerlcsh:Biology (General)CurcuminMedicinechemopreventionantitumor activity5-fluorouracilbusinesslcsh:QH301-705.5Therapeutic strategyJournal of Biological Research
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Desiccation resistance: effect of cuticular hydrocarbons and water content in Drosophila melanogaster adults

2018

Background.The insect cuticle covers the whole body and all appendages and has bi-directionnal selective permeability: it protects against environmental stress and pathogen infection and also helps to reduce water loss. The adult cuticle is often associated with a superficial layer of fatty acid-derived molecules such as waxes and long chain hydrocarbons that prevent rapid dehydration. The waterproofing properties of cuticular hydrocarbons (CHs) depend on their chain length and desaturation number. Drosophila CH biosynthesis involves an enzymatic pathway including several elongase and desaturase enzymes. Methods.The link between desiccation resistance and CH profile remains unclear, so we t…

CuticleDesaturaseAgricultural and Biological Sciences(all)EcologyDehydrationBiochemistry Genetics and Molecular Biology(all)Neuroscience(all)[SDV]Life Sciences [q-bio]lcsh:Rlcsh:Medicine/dk/atira/pure/subjectarea/asjc/1300Fat body/dk/atira/pure/subjectarea/asjc/1100GeneticsDrosophila/dk/atira/pure/subjectarea/asjc/2800Entomologydesaturase[SDV.AEN]Life Sciences [q-bio]/Food and NutritionInsectSelectionPeerJ
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Investigation on the Photosynthetic Membranes of Spruce Needles in Relation to the Occurrence of Novel Forest Decline II. The Content of QB-Protein, …

1988

In order to obtain an insight into the damage of thylakoid membranes of spruce (Picea abies) trees with damage of varying intensity, investigations were performed on the content of Qв-protein, cytochrome f, and P-700 in chloroplasts of spruce needles from apparently healthy and from damaged trees. Needles from the second and third needle year and the seventh whorl were chosen. The investigations were carried out in 1986 on a 20 to 25-year-old spruce plantation in the Hunsriick mountains and on an 80-year-old spruce plantation in the Westerwald mountains. In damaged trees an unequivocal decrease in the content of Qв-protein, cytochrome f, and P-700 was found, even in needle groups that appea…

Cytochrome fMembraneChemistryBotanyPhotosynthesisGeneral Biochemistry Genetics and Molecular BiologyZeitschrift für Naturforschung C
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Changes in the Content of Chlorophyll and Redox Components of the Thylakoid Membrane during Development and Senescence of Beech (Fagus sylvatica) Lea…

1995

Abstract Leaves from 145-year-old and 44-year-old beech trees were harvested during 1991-1993. Chlorophyll (Chl) and redox components of the thylakoid membrane, including P-700, cytochrome f (Cyt f) and D1 protein, were determined with the following results. Chl a + b, P-700 and Cyt f per unit of fresh weight (FW), dry weight (DW) and leaf area (LA) increase significantly during leaf development. This can be attributed to a massive membrane syn­thesis and new thylakoid formation in the cells. The Chl a/Chl b ratio decreases with the synthesis of Chl during the development of beech leaves and is reduced further with Chl breakdown in the stage of senescence. When expressed on the basis of Chl…

Cytochrome fbiologybiology.organism_classificationPhotosynthesisRedoxGeneral Biochemistry Genetics and Molecular Biologychemistry.chemical_compoundchemistryFagus sylvaticaDry weightChlorophyllThylakoidBotanyBeechZeitschrift für Naturforschung C
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